FROM I-55: Exit 150
Exit at #150 for Historic Ste. Genevieve. Turn east onto Hwy 32. Travel 4.6 miles to the intersection of Hwy 32 and Hwy 61. Continue straight through the stoplight and continue .9 mile to the intersection of Fourth and Market. Turn right on Market Street to enter the Historic District of Ste. Genevieve. Start your experience at the Welcome Center on the corner of Market Street and Main Street, where local guides can answer your questions, provide maps, coupons and discounted tour tickets.
Ste. Genevieve is just over 5 hours from Chicago. Follow I-55 S to St. Louis downtown. (approximately 4 hours). Continue south on I-55 for one hour (follow signs for 55 South to Memphis) and then follow the directions above for Exit 150 to Historic Ste Genevieve.
FROM KANSAS CITY, MO
Ste. Genevieve is an approximate 4 ½ hour drive from KC. Follow I-70 E to St. Louis (3.5 hours), exit onto I-270 South (follow signs for Memphis), and then take I-55 South to Ste. Genevieve (1 hour).
Follow I-55 N (approximately 3 ½ hours) to Exit #150 and then follow the directions from I-55 to the Historic District.
FROM SOUTHERN ILLINOIS
Cross the Mississippi River at Chester, IL. Continue on Highway 51 to Highway 61. Turn right to go north to Ste. Genevieve. Turn right on St. Marys Road to reach the Historic District of Ste. Genevieve.
Cross the Mississippi River at Cape Girardeau, MO. Continue on Highway 74 to I-55 N to Exit 150. Then follow the directions from I-55 to the Historic District.