Lodging Historic

Main Street Inn

221 North Main Street
Ste. Genevieve, MO 63670
availability button
Add to My Trip:

Originally built in 1882, as the Meyer Hotel, the Main Street Inn B&B has long been one of Missouri’s finest bed and breakfast establishments. After recently undergoing an extensive year-long renovation, the new owners and innkeeper are thrilled to re-open the Main Street Inn B&B and welcome our guests to what we hope will be a truly wonderful experience. If you are looking for a relaxing and peaceful getaway, the Main Street Inn B&B is the perfect destination.


Inn St. Gemme Beauvais (c1848)

78 North Main Street
Ste. Genevieve, MO 63670
St Gemme email
St Gemme FB
availability button
Add to My Trip:

Located in the heart of the historic district is the newly renovated Inn St. Gemme Beauvais. This Inn was built c1848 and is furnished beautifully in antiques. It offers themed king and queen suites with private baths, WIFI, cable, and DVDs.  Stay in The Garden Room, The Governor’s Chambers, or in the Hunter’s Glen for example. Full breakfasts are served.
Screen Shot 2016-08-16 at 10.13.31 AM

Noted as one of “11 Little Known Inns In Missouri That Offer An Unforgettable Overnight Stay”  Only in Your State


Dr. Hertich House (c1850)

99 North Main Street
Ste. Genevieve, MO 63670
airbnb.com/Ste. Genevieve
Add to My Trip:

Dr. Hertich House is a premiere Bed and Breakfast within walking distance of all major historic houses, historic sights and various restaurants.  This 1850 house was the residence and clinic of one of the first doctors in Sainte Genevieve. Newly restored


under new ownership, Dr. Hertich House is a luxury lodging perfect as a getaway for honeymooners, anniversaries and other special occasions. The Doctor’s House offers four, cozy three-room suites with king beds and gas burning fireplaces. The private bath has a relaxing 2-person jacuzzi tub. Each suite is also equipped with a mini fridge and microwave. The common area in the Dr. Hertich House has a coffee bar, breakfast items and games.  Each suite is listed separately on AirBnB.